Misitura Arowona: Anti-TB Drug Developed By UNILORIN PhD Student - |Ads4naira Blog|

Misitura Arowona: Anti-TB Drug Developed By UNILORIN PhD Student

A PhD student in the Department of Chemistry,
University of Ilorin, Misitura Arowona, has
developed a drug that promises to be potent in
the treatment of tuberculosis, an infectious
disease that usually attacks the lungs.
The University of Ilorin Bulletin, on Monday,
stated that the student, who is being supervised
by Prof. Joshua Obaleye, former Dean, Faculty of
Science of Unilorin, is currently undergoing a
sandwich fellowship at the Faculty of Science of
The Maharaja Sayajirao University, Vadodara,
India.
According to the publication, the metal attached
anti-TB drug developed by Arowona, has
improved the efficiency of the anti-TB drugs
compared to normal drugs that are consumed
globally.
“The country is ranked seventh among the 30
high TB burden countries and second in Africa
and the problem of TB in Nigeria has been made
worse by the issues of drug-resistant TB and the
HIV/AIDS.
“It is estimated that about 407, 000 people in
Nigeria have TB in a year,” it said.
The publication explained that Arowona, who is in
Vadodara for a year-long project, said, “Earlier
studies have proved that when a metal is
attached with a pharmaceutical, it increases the
efficacy of the drug.
“Taking a cue from cisplatin, an anti-cancer drug,
whose efficacy improved after applying platinum
as metal, the scholar worked on multiple metal-
based drugs to see whether the efficiency of anti-
TB drugs can be increased by attaching metals to
it”.
Also quoting a Professor of Chemistry,
Rajendrasinh Jadeja, of Sayajirao University, India,
the Nigerian scholar used metals like ion, cobalt,
copper and zinc to prepare the metallodrugs.
“The drugs, which have been developed, include
ciprofloxacin HCl, ofloxacin, pyrazinamide and
moxifloxacin HCl. Presently, there is no metal-
based anti-TB drug available in the market.
“When we compared the metallodrugs with the
original anti-TB drugs, the metallodrugs were
more effective.
“We did in-vitro test against bacteria. The metals
we have chosen are non-harmful to human
beings.
“Also, we found that of all the metallodrugs, the
copper complex of ciprofloxacin is most
effective.”

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